DigitalOcean Elevates its Agentic Inference Cloud with GPU Droplets powered by AMD Instinct MI350X GPUs
DigitalOcean and AMD collaborate to deliver new GPUs with lower latency and higher throughput for complex inference workloads
This is a Press Release edited by StorageNewsletter.com on February 24, 2026 at 2:00 pmDigitalOcean, an agentic inference cloud built for production AI at scale, announced the availability of new, high-performance GPU Droplets powered by AMD Instinc MI350X GPUs.
By integrating these GPUs into its agentic inference cloud, DigitalOcean continues to deliver cost-efficient, high-performance solutions for leading AI-native companies like ACE Studio to scale their inference workloads. Next quarter, DigitalOcean will also deploy AMD Instinct MI355X GPUs, marking the addition of liquid-cooled racks to their offering and further expanding access to accelerators specifically designed for larger datasets and models on their inference cloud.
Optimizing production inference with AMD Instinct MI350X GPUs
AMD Instinc MI350X Series GPUs set a new standard for generative AI and HPC. Built on the AMD CDNA 4 architecture, these GPUs deliver cutting-edge efficiency and performance for training massive AI models, high-speed inference, and complex HPC workloads including scientific simulations, data processing, and computational modeling. The capabilities of the GPUs allow DigitalOcean to optimize for compute bound prefill phase, while enabling high-performance inference at low latency and high token gen throughput. This provides the ability to load large models and larger context windows, leading to supporting a higher inference request density per GPU. Paired with DigitalOcean’s optimized inference platform, these feature enhancements of AMD Instinct MI350X GPUs offer lower latency and higher throughput.
“These results demonstrate that the DigitalOcean Agentic Inference Cloud isn’t just about providing raw compute, but about delivering the operational efficiency, inference optimizations, and scale required for demanding AI builders,” said Vinay Kumar, CPTO, DigitalOcean. “The availability of the AMD Instinc MI350X GPUs, combined with DigitalOcean’s inference optimized platform offers our customers a boost in performance and the massive memory capacity needed to run the world’s most complex AI workloads while delivering compelling unit economics.”
Earlier this year, DigitalOcean announced that by optimizing AMD Instinc GPUs, they were able to deliver 2X production request throughput and a 50% reduction in inference costs for Character.AI, a leading entertainment platform with one of the most demanding product inference workloads. Similarly, customers like ACE Studio are building with AMD Instinc MI350X GPUs to power complex inference workloads while managing costs. “At ACE Studio, our mission is to build an AI-driven music workstation for the future of music creation,” said Sean Zhao, co-founder & CTO. “As we expand our footprint on DigitalOcean, the next-gen AMD Instinct MI350X architecture, supported by close collaboration on inference optimization with AMD and DigitalOcean, provides us a strong foundation to push performance and cost efficiency even further for our customers.”
“Our collaboration with DigitalOcean is rooted in a shared commitment to pairing leadership AI infrastructure with a platform designed to make large-scale AI applications more accessible to the world’s most ambitious developers and enterprises,” said Negin Oliver, CVP, business development, data center GPU business, AMD. “By bringing the AMD Instinct MI350 Series GPUs to DigitalOcean’s Agentic Inference Cloud, we are empowering start-ups and enterprises alike to deploy and scale next-gen AI workloads with confidence.”
This initiative builds upon previous collaboration between DigitalOcean and AMD, including the launch of the AMD Developer Cloud and the release of AMD Instinct MI300X and MI325X GPUs on DigitalOcean last year.
Enterprise performance with predictable cost-efficiency and simple operations at the forefront
In addition to offering the latest AMD GPUs, DigitalOcean maintains its commitment to transparency and simplicity, ensuring this powerful technology is easy to adopt for developers and emerging businesses:
- Cost-effective, predictable pricing: DigitalOcean offers transparent, usage based pricing with flexible contracts and no hidden fees
- Simple setup: GPU Droplets can be provisioned and configured with security, storage, and networking requirements in just a few clicks, drastically simplifying deployment compared to complex cloud environments
- Access to enterprise features: GPU Droplets offer enterprise-grade SLAs, observability features, and are HIPAA-eligible and SOC 2 compliant
The new GPU Droplets powered by AMD Instinc MI350X are available in the Atlanta Region Datacenter.






