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AWS re:Invent 2025: Amazon EC2 P6e-GB300 UltraServers Accelerated by Nvidia GB300 NVL72 are Now Generally Available

New Nvidia instances also available on AWS

This is a Press Release edited by StorageNewsletter.com on December 5, 2025 at 2:01 pm

AWS announces the general availability of Amazon Elastic Compute Cloud (Amazon EC2) P6e-GB300 UltraServers.P6e-GB300 UltraServers, accelerated by NVIDIA GB300 NVL72, provide 1.5x GPU memory and 1.5x FP4 compute (without sparsity) compared to P6e-GB200. 

Customers can optimize performance for the most powerful models in production with P6e-GB300 for applications that require higher context and implement emerging inference techniques like reasoning and Agentic AI.

To get started with P6e-GB300 UltraServers, please contact your AWS sales representative.

To learn more about P6e UltraServers and instances, visit Amazon EC2 P6 instances.

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