HPE Discover 2025: HPE Expands ProLiant Gen12 Server Portfolio

At HPE Discover Las Vegas 2025, HPE announced an expansion to the ProLiant Compute Gen12 server portfolio, which delivers next-level security, performance and efficiency.

The expanded portfolio includes 2 new servers powered by 5^th Gen AMD EPYC processors to optimize memory-intensive workloads, and new automation features for greater visibility and control delivered through HPE Compute Ops Management.

In addition, ProLiant Compute servers are available with HPE Morpheus VM Essentials software support. Morpheus VM Essentials is an open virtualization solution that helps reduce costs, minimize vendor lock-in, and simplify IT management. The company also announced new HPE for Azure Local solutions with the ProLiant DL145 Gen11 server to empower expansion of purpose-built edge capabilities across distributed environments.

“Enterprise workloads are growing and evolving, requiring next-generation technologies that maximize IT environments, securely and efficiently,” said Krista Satterthwaite, SVP and GM, compute, HPE. “The enhanced HPE ProLiant Compute Gen12 portfolio, which now includes new servers powered by 5^th Gen AMD EPYC processors, drives even greater optimized workload performance, security protection from the chip-to-the-cloud, and a boost to productivity with AI-driven management capabilities.”

HPE delivers double the memory with new ProLiant Gen12 servers
The company added 2 new servers to the ProLiant Gen12 portfolio: the ProLiant Compute DL325 and DL345 Gen12 servers with latest AMD EPYC processors.

The new servers are optimized to handle memory-intensive workloads, such as virtualization and edge deployments, with twice as much memory – up to 6TB – compared to the previous-gen. ⁽¹⁾

The new servers feature the next-gen HPE Integrated Lights-Out (HPE iLO 7), the firm’s security IP that builds in protection at the silicon level to protect against threats.

The latest version now safeguards the server at the factory floor during assembly to continue all the way through a server’s end-of-life and includes protection against future quantum computing attacks.

Simplifying management and boosting productivity with enhanced automation features through HPE Compute Ops Management
The firm also announced new automated and AI-driven features for HPE Compute Ops Management, a secure, cloud-based software application to monitor and manage servers.

Available on all ProLiant Compute Gen12 servers, these new features offer customers a number of benefits across their environment:

Enhanced insights – New tool allows customers to view HPE Active Health System files within HPE Compute Ops Management to expedite root cause analysis, avoid opening support tickets, and greatly reduce mean time to resolution
Reduced complexity –Integration of multi-vendor server monitoring into existing environments to help simplify operations, decrease the number of tools required for daily activities and achieve a consolidated view of the entire compute infrastructure
Decreased downtime – Gain AI-driven insights with workflow policy approvals to safeguard against major disruptive operations often caused by human error. Latest feature ensures that policies are verified and necessary layers of action approval are in place to prevent downtime

HPE Compute Ops Management is already helping customers simplify server management, dramatically reducing manual effort in deployment. Improvements include ⁽²⁾:

Up to 75% less time spent managing servers
Up to 4.8 hours less downtime per server/year
Up to $152,000 in travel and software costs saved over 3 years

Modernizing and optimizing costs with Morpheus VM Essentials Software
The company is further simplifying IT management for customers by enabling Morpheus VM Essentials Software on the latest ProLiant servers. With the virtualized solution, customers can achieve higher performance for virtualized workloads while saving space and energy, and reducing licensing costs by up to 90%. ⁽³⁾

ProLiant Compute Gen12 servers featuring AMD EPYC processors offer performance and power efficiency with Morpheus VM Essentials. (Additional details can be found here: Driving Virtualization Forward: The Power of AMD and HPE Morpheus VM Essentials Software).

Empowering virtualization at edge with integration through ProLiant DL145 for Azure Local Integrated System

Additionally, HPE announced that the ProLiant DL145 Gen11 server, engineered for the edge and featuring AMD EPYC processors, is now available as an HPE Integrated System for Azure Local for integration between on-premises infrastructure and cloud services.

The ProLiant DL145 Gen11 server is compact, resilient, quiet, and adaptable to fit on any tabletop, wall, or cabinet, making it for any edge environment across retail, financial services, manufacturing, and healthcare.

The server is easy to deploy with plug-and-play installation and blends in seamlessly in a customer’s environment while delivering high performance for data processing and real-time insights.

The ProLiant DL145 Gen11 servers also offer Compute Ops Management to securely access, monitor, and manage servers, no matter where they live, and are pre-configured with the latest software and security updates to deploy systems quickly.

Availability:

ProLiant DL145 for Azure Local Integrated System is available.
ProLiant Compute DL325 and DL345 Gen12 servers are available for order and will ship in July.
HPE Morpheus VM Essentials software is available.

⁽¹⁾ Based on comparison between HPE ProLiant Compute DL325 and DL345 Gen11 servers using 5th Gen AMD EPYC processors with up to 3TB memory.
⁽²⁾ Based on customer feedback study from Forrester Consulting, New Technology: The Projected Total Economic Impact of HPE Compute Ops Management, commissioned by HPE (June 2024).
⁽³⁾ Based on internal analysis of the cost of HPE Morpheus VM Essentials licensing versus available market data on cost of existing virtualization licensing. Savings do not include discounts and subject to change without notice.